Genetic Equipments

Ion S5™ XL System

The Ion S5™ XL next-generation sequencing system enables a simple targeted sequencing workflow with reliable performance and industry-leading speed. The Ion S5 XL System leverages the speed of semiconductor sequencing with impressive computing power found both on-board and in the included Torrent Server, to produce high quality sequencing data in as little as 2.5 hours and enable you to go from DNA library to data in as little as 24 hours with only 45 minutes of total hands-on time on the Ion Chef™ System and the Ion S5 XL System. The Ion S5 XL System is simple to use with cartridge-based reagents and offers superior scalability and flexibility to support a broad range of high throughput sequencing applications, from microbial genomes and gene panels to exomes and transcriptomes, using our 5 Series chips.

AxioScope A1

Axio Scope.A1 для биологии

AxioScope A1 A modular microscope is suitable for a full range of diverse tasks. You can use it in different fields of medicine and biology. There are 23 basic versions of the tripod. The thickness of the samples can be from very small to 380 millimeters.

Application:

  • Hematology
  • Cytology
  • Histology
  • Microbiology
  • Helminthology
  • Immunology
  • Bacteriology
  • Genetics

InnoScan 710 - 2-colour Fluorescence Microarray Scanner

 

Characterised by its ease-of-use, speed and image quality, InnoScan®710 is an ideal tool for routine microarray reading.

• High precision - maximum resolution of 3 µm/pixel 
• The fastest system on the market (10 to 35 lines/sec) 
• Reading time less than 4 minutes at 10µm resolution 
• Simple to use and easy to understand 
• Reliable sample identification by barcode 
• Convenient, compact, portable design 
• Very competitive price

InnoScan®710 is a fluorescence scanner 2 colors (635nm and 532nm), including a barcode reader, suitable for all microarrays (nucleic acid, protein, cells and tissues arrays) spotted on standard slides combining performance with cost-effectiveness for a variety of applications (gene expression, genotyping, aCGH, ChIP-chip, microRNA, DNA Methylation, proteomic, custom arrays).
InnoScan®710 has a special feature of using a real-time autofocus system that offers the advantage of making it insensitive to substrate distortion and so making the entire reading area completely uniform. InnoScan scanners are 
well known for their excellent photometric properties, particularly in terms of sensitivity and signal-to-noise ratio.
Their autofocusing system combined with a true "pinhole" confocal detection, based on 2 fast and extremely sensitive digital photomultiplier(s) (PMT) and high accuracy optical filtration confer excellent photometric performance to InnoScan®710, notably in terms of its sensitivity and signal-to-noise ratio. 
Able to scan simultaneously the 2 detection channels in 3.5 minutes (at 10μm/pixel,full scan area), thanks to its 
patented XY motorization, InnoScan®710 is the quickest scanner on the market with a flexible scanning speed from 
10 to 35 lines per seconds.
Due to its optical system and its improved sensitivity, InnoScan®710 is able to scan a high density microarray while keeping high quality image. The pixel size is adjustable from 3 to 40 μm. Its image analysis software Mapix® has been imagined in order to optimize the high volume file management. 
The linear variation of PMT gain associated with Mapix® histograms offers in real-time accurate adjustment for saturation levels and a easy channel balacing.
InnoScan®710 has been designed to be easily transportable thanks to its robust conception, studied dimensions and light weight (15.5Kg only). 
InnoScan®710 is delivered with a validation tool and a software to check the scanner performances. 
InnoScan®710 comes with intuitive and easy-to-use Mapix® software. 
Mapix® do acquisition, image analysis and data export to other standard software well-know in the market. It is fully compatible with Windows and Linux operating systems (32 and 64-bit) and with Mac soon. 
Its Ethernet plug allows an utilization and a data sharing between different users through a network.

The glycosylated hemoglobin D-10 analyzer is designed for automatic monitoring of diabetes and beta-thalassemia in one compact platform. The device accurately analyzes the level of specific hemoglobin groups in whole blood, allowing for a comprehensive analysis.

Mass spectrometr SEQUENOM

Mass-spektrometr

Sequenom SNP genotyping uses a bead-less and label-free primer-extension chemistry to generate allele-specific products with distinct masses. The backbone of its high-throughput detection capabilities is the speed and accuracy of Matrix-Assisted Laser Desorption/Ionization Time-Of-Flight mass spectrometry (MALDI-TOF MS). Allele discrimination is conferred by primer extension with a high-fidelity polymerase enzyme across the SNP site, leading to differences in mass of extended products. Differentiation of genotypes for each of the SNPs multiplexed in one assay is a result of unique mass ranges for the extension primers.

The Genomics Platform currently offers Sequenom's hME technology, allowing the rapid design and deployment of pooled assays with up to seven SNPs, and Sequenom's higher complexity iPLEX technology, where up to 36 SNPs are simultaneously assayed.

Assays available
hME: any number of custom SNPs in pooled assays of up to 7 SNPs
iPLEX: any number of custom SNPs in pooled assays of up to 36 SNPs

Details about Sequenom technology
Sequenom technology combines a homogeneous reaction format with standardized assay conditions. Each assay has a single extension primer to interrogate both alleles, minimizing the total number of reactions required.

The MassEXTEND reaction has three levels of biological stringency:

  • Polymerase chain reaction (PCR) target amplification
  • Extension primer binding
  • Primer extension across polymorphic base(s) with a high-fidelity DNA polymerase enzyme

Minimum requirements

A minimum of 100,000 planned genotypes (samples x SNPs) is required for new projects

Bio Rad D10

 

D-10 Instrumentation

Features

Wide opportunities

• Easy switching between analysis modes on HbA1c and β-thalassemia without a change in reagents or cartridges

• Fast 3-minute analysis program on HbA1c

• Complete assay program for β-thalassemia, including results analysis on HbA1c

• In the case of increasing research flows, to the D-10 ™ Rack Loader tripod system

Complex analysis

• Analysis for β-thalassemia and diabetes • Simultaneous quantification of HbA2, HbF and HbA1c

• Accurate results for HbA2 and HbF in just 6.5 minutes • Detection of variant forms of hemoglobins

• Ability to determine HbA1c in the presence of hemoglobins S, C, D and E

Easy to use

• Touch screen control

• Fully automated bar code reading and fence samples from a primary tube

• Simple maintenance